Filgotinib | CAS 1206161-97-8
High-quality Pharmaceutical Intermediates & APIs supplied by Jinan Shenghe Chemical Co., Ltd. Competitive pricing, reliable delivery, and full technical support for B2B buyers worldwide.
Detailed Chemical Properties & Synonyms
Applications / Uses
体外研究:在细胞系中，GLPG0634抑制IL-2和IL-4诱导的JAK1/JAK3/γc信号和IFN-αB2诱导的JAK1/TYK2 II型受体信号，IC50值范围为150 到760 nM。GLPG0634对JAK/STAT信号中JAK1激酶比对JAK2激酶在细胞水平上显示出更高的选择性。此外，GLPG0634也会抑制Th1，Th2，和Th17细胞的分化。 体内研究:口服给药后，大鼠体内的绝对生物利用度适中(45%)，而小鼠体内很高(～100%)。在大鼠和小鼠CIA模型中，Filgotinib (
Product Overview
| Product Name | Filgotinib |
|---|---|
| CAS Number | 1206161-97-8 |
| Category | Pharmaceutical Intermediates & APIs |
| Supplier | Jinan Shenghe Chemical Co., Ltd. |
Description
Filgotinib (CAS 1206161-97-8) is a Pharmaceutical Intermediates & APIs product supplied by Jinan Shenghe Chemical Co., Ltd. We provide consistent-quality Filgotinib to global B2B buyers, with stable supply, competitive pricing and full documentation (COA, MSDS, TDS).
Applications
As a reliable pharmaceutical intermediates & apis raw material, Filgotinib is widely used in fine chemical synthesis, pharmaceutical intermediates and specialty formulation. Specific grades and specifications are available on request.
Packaging & Storage
Available in 25 kg / 200 kg drums or IBC totes. Store in a cool, dry, well-ventilated place, away from incompatible substances. Keep container tightly closed.
Quality & Documentation
Every batch is delivered with Certificate of Analysis (COA), Material Safety Data Sheet (MSDS) and Technical Data Sheet (TDS). Stable supply and competitive pricing for global B2B buyers.
Request a Quote
Synonyms & Trade Names
Filgotinib (GLPG0634), SYN1158, N-(5-(4-((1,1-Dioxidothiomorpholino)methyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide, N-[5-[4-[(1,1-Dioxido-4-thiomorpholinyl)methyl]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide, CyclopropanecarboxaMide, N-[5-[4-[(1,1-dioxido-4-thioMorpholinyl)Methyl]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]-
Applications
体外研究:在细胞系中，GLPG0634抑制IL-2和IL-4诱导的JAK1/JAK3/γc信号和IFN-αB2诱导的JAK1/TYK2 II型受体信号，IC50值范围为150 到760 nM。GLPG0634对JAK/STAT信号中JAK1激酶比对JAK2激酶在细胞水平上显示出更高的选择性。此外，GLPG0634也会抑制Th1，Th2，和Th17细胞的分化。 体内研究:口服给药后，大鼠体内的绝对生物利用度适中(45%)，而小鼠体内很高(～100%)。在大鼠和小鼠CIA模型中，Filgotinib (
Packaging & Shipping
- Standard: 25 kg fiber drum / 200 kg steel drum with double PE liner
- Small pack: 1 kg / 5 kg aluminum foil bag for lab & sample
- Custom: packaging size and labeling per customer requirement
- Lead time: in-stock items ship within 3-5 business days
- Documents: COA, MSDS / SDS, TDS provided with every shipment
- Global: air, sea (FCL / LCL) and express to 80+ countries
Storage & Handling
Store in a cool, dry, well-ventilated place away from heat, direct sunlight and incompatible materials. Keep container tightly closed. Use appropriate personal protective equipment and refer to the SDS for full safety guidance before handling.
Frequently Asked Questions
Yes. A batch-specific COA and free or charged sample are available on request before bulk ordering.
Yes. We offer custom grade, particle size and purity adjustment based on your application and order volume.
MOQ depends on the product; small quantities are supported for R&D and trial runs.
Every batch is tested in-house and retains full traceability from raw material to finished goods.
Why Choose Jinan Shenghe Chemical
Request a Quote
Looking for pricing, availability or technical data for Filgotinib?
Email us at sales@shenghechemical.com or use the button above. Our team typically responds within 1 business day.
About Jinan Shenghe Chemical Co., Ltd.
Jinan Shenghe Chemical Co., Ltd.
We are a professional chemical supplier based in Jinan, China. Since 2013, we have been connecting manufacturers and global B2B buyers with reliable sourcing, quality-controlled products and efficient logistics.
Our business covers food & feed additives, fine chemicals, pharmaceutical intermediates, eco-materials, coatings and specialty chemicals — all non-hazardous and compliant with our licensed scope.